2018年度業績

英文論文
  1. Iwashita T, Nakai Y, Mukai T, Togawa O, Matsubara S, Hatano Y, Hara A, Tanaka M, Shibahara J, Fukayama M, Isayama H, Yasuda I.A 19-Gauge Histology Needle Versus a 19-Gauge Standard Needle in Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Solid Lesions: A Multicenter Randomized Comparison Study (GREATER Study). Dig Dis Sci. 2018;63(4):1043-1051. doi: 10.1007/s10620-018-4913-y. PMID: 29464585.
  2. Abe H, Saito R, Ichimura T, Iwasaki A, Yamazawa S, Shinozaki-Ushiku A, Morikawa T, Ushiku T, Yamashita H, Seto Y, Fukayama M. CD47 expression in Epstein-Barr virus-associated gastric carcinoma: coexistence with tumor immunity lowering the ratio of CD8+/Foxp3+ T cells. Virchows Arch. 2018;472(4):643-651. doi: 10.1007/s00428-018-2332-2. PMID: 29536167.
  3. Nakagama Y, Inuzuka R, Ichimura KHinata M, Takehara H, Takeda N, Kakiuchi S, Shiraga K, Asakai H, Shindo T, Hirata Y, Saitoh M, Oka A. Accelerated Cardiomyocyte Proliferation in the Heart of a Neonate With LEOPARD Syndrome-Associated Fatal Cardiomyopathy. Circ Heart Fail. 2018;11(4) DOI:10.1161/CIRCHEARTFAILURE.117.004660. PMID: 29602897.
  4. Murono K, Kawai K, Hata K, Emoto S, Kaneko M, Sasaki K, Nishikawa T, Otani K, Tanaka T, Ikemura M, Nozawa H. A case of anastomotic stenosis of the small intesine caused by cholesterol cyrstal embolisum. Surg Case Rep. 2018;4(1):29. doi: 10.1186/s40792-018-0442-3.
  5. Ohki D, Tsuji Y, Shinozaki T, Sakaguchi Y, Minatsuki C, Kinoshita H, Niimi K, Ono S, Hayakawa Y, Yoshida S, Yamada A, Kodashima S, Yamamichi N, Hirata Y, O T, Fujishiro M, Fukayama M, Koike K. Sessile serrated adenoma detection rate is correlated with adenoma detection rate.
  6. World J Gastrointest Oncol. 2018;10(3):82-90. doi: 10.4251/wjgo.v10.i3.82. PMID: 29564038.
    Choi WT, Brown I, Ushiku T, Yozu M, Setia N, Srivastava A, Johncilla M, Pai RK, Gill RM, Fukayama M, Misdraji J, Lauwers GY. Gastric pyloric gland adenoma: a multicentre clinicopathological study of 67 cases. Histopathology. 2018;72(6):1007-1014. doi: 10.1111/his.13460. PMID: 29278427.
    Makise N, Sekimizu M, Kubo T, Wakai S, Hiraoka N, Komiyama M, Fukayama M, Kawai A, Ichikawa H, Yoshida A. Clarifying the Distinction Between Malignant Peripheral Nerve Sheath Tumor and Dedifferentiated Liposarcoma: A Critical Reappraisal of the Diagnostic Utility of MDM2 and H3K27me3 Status. Am J Surg Pathol. 2018;42(5):656-664. doi: 10.1097/PAS.0000000000001014. PMID: 29309298.
  7. Okuno T, Kawai K, Koyama K, Takahashi M, Ishihara S, Momose T, Morikawa T, Fukayama M, Watanabe T. Value of FDG-PET/CT Volumetry After Chemoradiotherapy in Rectal Cancer. Dis Colon Rectum. 2018;61(3):320-327. doi: 10.1097/DCR.0000000000000959. PMID: 29360680.
  8. Niikura R, Hayakawa Y, Hirata Y, Konishi M, Suzuki N, Ihara S, Yamada A, Ushiku T, Fujishiro M, Fukayama M, Koike K. Distinct Chemopreventive Effects of Aspirin in Diffuse and Intestinal-Type Gastric Cancer. Cancer Prev Res (Phila). 2018;11(5):279-286. doi: 10.1158/1940-6207.CAPR-17-0276. PMID: 29453233.
    Kunita A, Baeriswyl V, Meda C, Cabuy E, Takeshita K, Giraudo E, Wicki A, Fukayama M, Christofori G. Inflammatory Cytokines Induce Podoplanin Expression at the Tumor Invasive Front. Am J Pathol. 2018;188(5):1276-1288. doi: 10.1016/j.ajpath.2018.01.016. PMID: 29458011.
  9. Saito K, Isayama H, Sakamoto Y, Nakai Y, Ishigaki K, Tanaka M, Watadani T, Arita J, Takahara N, Mizuno S, Kogure H, Ijichi H, Tateishi K, Tada M, Hasegawa K, Fukayama M, Kokudo N, Koike K. A phase II trial of gemcitabine, S-1 and LV combination (GSL) neoadjuvant chemotherapy for patients with borderline resectable and locally advanced pancreatic cancer. Med Oncol. 2018;35(7):100. doi: 10.1007/s12032-018-1158-8. PMID: 29846849.
  10. Yonenaga A, Hasumi E, Fujiu K, Ushiku A, Hatano M, Ando J, Morita H, Watanabe M, Komuro I.
  11. Prognostic Improvement of Acute Necrotizing Eosinophilic Myocarditis (ANEM) Through a Rapid Pathological Diagnosis and Appropriate Therapy. Int Heart J. 2018;59(3):641-646. doi: 10.1536/ihj.17-308. PMID: 29628475.
  12. Suzuki Y, Koya J, Ebisawa K, Abe H, Shinozaki-Ushiku A, Nakamura F, Kurokawa M. Sequential development of monoclonal B cell lymphocytosis-derived small lymphocytic lymphoma and plasma cell leukemia. Ann Hematol. 2018;97(5):917-919. doi: 10.1007/s00277-018-3248-2. PMID: 29417202.
  13. Yoshida A, Makise N, Wakai S, Kawai A, Hiraoka N. INSM1 expression and its diagnostic significance in extraskeletal myxoid chondrosarcoma. Mod Pathol. 2018;31(5):744-752. doi: 10.1038/modpathol.2017.189. PMID: 29327709.
  14. Nakai Y, Gonoi W, Hagiwara A, Nishioka Y, Abe H, Shindoh J, Hasegawa K. MRI Detection of Intratumoral Fat in Colorectal Liver Metastases After Preoperative Chemotherapy. AJR Am J Roentgenol. 2018;210(5):W196-W204. doi: 10.2214/AJR.17.18814. PMID: 29629795.
  15. Kunita A, Morita S, Irisa TU, Goto A, Niki T, Takai D, Nakajima J, Fukayama M. MicroRNA-21 in cancer-associated fibroblasts supports lung adenocarcinoma progression. Sci Rep. 2018;8(1):8838. doi: 10.1038/s41598-018-27128-3. PMID: 29892003.
  16. Tanaka A, Ishikawa S, Ushiku T, Yamazawa S, Katoh H, Hayashi A, Kunita A, Fukayama M. Frequent CLDN18-ARHGAP fusion in highly metastatic diffuse-type gastric cancer with relatively early onset. Oncotarget. 2018;9(50):29336-29350. doi: 10.18632/oncotarget.25464. eCollection 2018 Jun 29. PMID: 30034621.
  17. Furuya G, Abe H, Shinozaki-Ushiku A, Yamashita A, Ihara S, Hirata Y, Chiba A, Fujioka Y, Kurokawa M, Koike K, Fukayama M. Extranodal NK/T-cell lymphoma of the nasal cavity developed in a patient with intestinal Epstein-Barr virus-positive T/NK-cell lymphoproliferative disorder. Pathol Res Pract. 2018;214(7):1051-1055. doi: 10.1016/j.prp.2018.05.022. PMID: 29843925.
  18. Tanaka M, Ushiku T, Ikemura M, Takazawa Y, Igari T, Shimizu M, Yamaguchi H, Fukushima N, Sakuma K, Arita J, Sakamoto Y, Hasegawa K, Watadani T, Nakai Y, Koike K, Fukayama M. Pancreatic Lipomatous Hamartoma: A Hitherto Unrecognized Variant. Am J Surg Pathol. 2018;42(7):891-897. doi: 10.1097/PAS.0000000000001075. PMID: 29738363.
  19. Tsukui D, Kanda H, Shinozaki-Ushiku A, Tateishi S, Takeshima Y, Nagafuchi Y, Sasaki O, Iwasaki Y, Harada H, Shibuya M, Sumitomo S, Shoda H, Kubo K, Fujio K, Nakamura F, Kurokawa M, Fukayama M, Yamamoto K. Polymorphic lymphoproliferative disorders in patients with rheumatoid arthritis are associated with a better clinical outcome. Mod Rheumatol. 2018;28(4):621-625. doi: 10.1080/14397595.2017.1387223. PMID: 29057700.
  20. Makise N, Sekimizu M, Kubo T, Wakai S, Watanabe SI, Kato T, Kinoshita T, Hiraoka N, Fukayama M, Kawai A, Ichikawa H, Yoshida A. Extraskeletal osteosarcoma: MDM2 and H3K27me3 analysis of 19 cases suggest disease heterogeneity. Histopathology. 2018;73(1):147-156.
  21. doi: 10.1111/his.13506. PMID: 29489027.
  22. Suzuki Y, Honda A, Nakazaki K, Mizuno H, Ikemura M, Shinozaki-Ushiku A, Nakamura F, Fukayama M, Kurokawa M. Histological transformation of MALT lymphoma to plasma cell leukemia after rituximab-containing therapy. Ann Hematol. 2018;97(7):1297-1298. doi: 10.1007/s00277-018-3300-2. PMID: 29582109.
  23. Sato M, Taguchi A, Fukui Y, Kawata A, Taguchi S, Kashiyama T, Eguchi S, Inoue T, Tomio K, Tanikawa M, Sone K, Mori M, Nagasaka K, Adachi K, Ikemura M, Domoto Y, Arimoto T, Oda K, Fukayama M, Osuga Y, Fujii T. Blood Vessel Invasion Is a Strong Predictor of Postoperative Recurrence in Endometrial Cancer. Int J Gynecol Cancer. 2018;28(5):875-881. doi: 10.1097/IGC.0000000000001262. PMID: 29664845.
  24. Kage H, Kohsaka S, Shinozaki-Ushiku A, Ushiku T, Takai D, Nakajima J, Miyagawa K, Aburatani H, Mano H, Nagase T. Spontaneous Transformation from EGFR and ALK Wild-Type Lung Adenocarcinoma to Neuroendocrine Carcinoma. J Thorac Oncol. 2018;13(7):e126-e128. doi: 10.1016/j.jtho.2018.02.029. PMID: 29935853.
  25. Kawazoe Y, Shimamoto K, Yamaguchi R, Shintani-Domoto Y, Uozaki H, Fukayama M, Ohe K
  26. Faster R-CNN-Based Glomerular Detection in Multistained Human Whole Slide Images J. Imaging. 2018;4(7):91(1-19). doi:10.3390/jimaging4070091.
  27. Yasunaga M, Taoka K, Nakagawa H, Yamada A, Abe H, Jona M, Nishikawa M, Nakazaki K, Yatomi Y, Fukayama M, Koike K, Kurokawa M. Eculizumab treatment for ischemic enteritis accompanied with paroxysmal nocturnal hemoglobinuria: a case report and literature review. Ann Hematol. 2018;97(8):1513-1515. DOI: 10.1007/s00277-018-3286-9. PMID: 29532162.
  28. Fujiwara N, Nakagawa H, Enooku K, Kudo Y, Hayata Y, Nakatsuka T, Tanaka Y, Tateishi R, Hikiba Y, Misumi K, Tanaka M, Hayashi A, Shibahara J, Fukayama M, Arita J, Hasegawa K, Hirschfield H, Hoshida Y, Hirata Y, Otsuka M, Tateishi K, Koike K. CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity. Gut 2018;67(8):1493-1504. doi: 10.1136/gutjnl-2017-315193. PMID: 29437870.
  29. Tainaka K, Murakami TC, Susaki EA, Shimizu C, Saito R, Takahashi K, Hayashi-Takagi A, Sekiya H, Arima Y, Nojima S, Ikemura M, Ushiku T, Shimizu Y, Murakami M, Tanaka KF, Iino M, Kasai H, Sasaoka T, Kobayashi K, Miyazono K, Morii E, Isa T, Fukayama M, Kakita A, Ueda HR. Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents. Cell Rep. 2018;24(8):2196-2210.e9. doi: 10.1016/j.celrep.2018.07.056. PMID: 30134179.
  30. Aoki T, Yamada A, Takahashi M, Niikura R, Toyama K, Ushiku T, Kurokawa M, Momose T, Fukayama M, Koike K. Development and internal validation of a risk scoring system for gastrointestinal events requiring surgery in gastrointestinal lymphoma patients. J Gastroenterol Hepatol. 2018. [Epub ahead of print] doi: 10.1111/jgh.14452. PMID: 30151937.
  31. Karasaki T, Qiang G, Anraku M, Sun Y, Shinozaki-Ushiku A, Sato E, Kashiwabara K, Nagayama K, Nitadori JI, Sato M, Murakawa T, Kakimi K, Fukayama M, Nakajima J. High CCR4 expression in the tumor microenvironment is a poor prognostic indicator in lung adenocarcinoma. J Thorac Dis. 2018;10(8):4741-4750. doi: 10.21037/jtd.2018.07.45. PMID: 30233846.
  32. Miyama Y, Morikawa T, Miyakawa J, Koyama Y, Kawai T, Kume H, Fukayama M. The prognostic value of PD-L1 expression in upper tract urothelial carcinoma varies according to platelet count. Cancer Med. 2018;7(9):4330-4338. doi: 10.1002/cam4.1686. PMID: 30062756.
  33. Nakatsuka T, Soroida Y, Nakagawa H, Shindo T, Sato M, Soma K, Nakagomi R, Kobayashi T, Endo M, Hikita H, Sato M, Gotoh H, Iwai T, Yasui M, Shinozaki-Ushiku A, Shiraga K, Asakai H, Hirata Y, Fukayama M, Ikeda H, Yatomi Y, Tateishi R, Inuzuka R, Koike K. Identification of liver fibrosis using the hepatic vein waveform in patients with Fontan circulation. Hepatol Res. 2018. [Epub ahead of print] doi: 10.1111/hepr.13248. PMID: 30182424.
  34. Ito K, Sakamoto Y, Isayama H, Nakai Y, Watadani T, Tanaka M, Ushiku T, Akamatsu N, Kaneko J, Arita J, Hasegawa K, Kokudo N. The Impact of MDCT and Endoscopic Transpapillary Mapping Biopsy to Predict Longitudinal Spread of Extrahepatic Cholangiocarcinoma. J Gastrointest Surg. 2018;22(9):1528-1537. doi: 10.1007/s11605-018-3793-y. PMID: 29766443.
  35. Hiroyoshi J, Yamashita S, Tanaka M, Hayashi A, Ushiku T, Kaneko J, Akamatsu N, Arita J, Sakamoto Y, Hasegawa K. Contrast-enhanced intraoperative ultrasound in the resection of colorectal liver metastases with intrabiliary growth. Clin J Gastroenterol. 2018;11(5):348-353. doi: 10.1007/s12328-018-0858-0. PMID: 29633083.
  36. Urabe M, Ushiku T, Shinozaki-Ushiku A, Iwasaki A, Yamazawa S, Yamashita H, Seto Y, Fukayama M. Adenocarcinoma of the esophagogastric junction and its background mucosal pathology: A comparative analysis according to Siewert classification in a Japanese cohort. Cancer Med. 2018;7(10):5145-5154. doi: 10.1002/cam4.1763. PMID: 30239168.
  37. Makise N, Sekimizu M, Konishi E, Motoi T, Kubo T, Ikoma H, Watanabe SI, Okuma T, Hiraoka N, Fukayama M, Kawai A, Ichikawa H, Yoshida A. H3K27me3 deficiency defines a subset of dedifferentiated chondrosarcomas with characteristic clinicopathological features. Mod Pathol. 2018. [Epub ahead of print] doi: 10.1038/s41379-018-0140-5. PMID: 30291346.
  38. Shinagawa T, Hata K, Morikawa T, Takiyama H, Emoto S, Murono K, Kaneko M, Sasaki K, Nishikawa T, Tanaka T, Kawai K, Fukayama M, Nozawa H. Pine-cone and villi patterns are endoscopic signs suggestive of ulcerative colitis-associated colorectal cancer and dysplasia. Gastrointest Endosc. 2018;pii: S0016-5107(18)33165-1 doi: 10.1016/j.gie.2018.09.037. PMID: 30326231.
  39. Karakawa A, Taoka K, Kaburaki T, Tanaka R, Shinozaki-Ushiku A, Hayashi H, Miyagi-Maeshima A, Nishimura Y, Uekusa T, Kojima Y, Fukayama M, Kurokawa M, Aihara M. Clinical features and outcomes of secondary intraocular lymphoma. Br J Haematol. 2018;183(4):668-671. doi: 10.1111/bjh.15005. PMID: 29143310.
  40. Li Z, Maeda D, Kudo-Asabe Y, Tamura D, Nanjo H, Hayashi A, Ikemura M, Fukayama M, Goto A. MED12 is frequently mutated in ovarian and other adnexal leiomyomas. Hum Pathol. 2018;81:89-95. doi: 10.1016/j.humpath.2018.06.013. PMID: 29944972.
  41. Toya T, Ogura M, Toyama K, Yoshimi A, Shinozaki-Ushiku A, Honda A, Honda K, Hosoya N, Murakami Y, Kawashima H, Nannya Y, Arai S, Nakamura F, Shinoda Y, Nangaku M, Miyagawa K, Fukayama M, Moriya-Saito A, Katayama I, Ogura T, Kurokawa M. Prognostic factors of Erdheim-Chester disease: a nationwide survey in Japan. Haematologica. 2018;103(11):1815-1824. doi: 10.3324/haematol.2018.190728. PMID: 29976744.
  42. Hayakawa Y, Tsuboi M, Asfaha S, Kinoshita H, Niikura R, Konishi M, Hata M, Oya Y, Kim W, Middelhoff M, Hikiba Y, Higashijima N, Ihara S, Ushiku T, Fukayama M, Tailor Y, Hirata Y, Guha C, Yan KS, Koike K, Wang TC. BHLHA15-positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice. Gastroenterology. 2018;pii: S0016-5085(18)35272-7. doi: 10.1053/j.gastro.2018.11.024. PMID: 30448068.
  43. Rokutan H, Abe H, Nakamura H, Ushiku T, Arakawa E, Hosoda F, Yachida S, Tsuji Y, Fujishiro M, Koike K, Totoki Y, Fukayama M, Shibata T. Initial and crucial genetic events in intestinal-type gastric intramucosal neoplasia. J Pathol. 2018. [Epub ahead of print] doi: 10.1002/path.5208. PMID: 30474112.
  44. Kinoshita Y, Takashi Y, Ito N, Ikegawa S, Mano H, Ushiku T, Fukayama M, Nangaku M, Fukumoto S. Ectopic expression of Klotho in fibroblast growth factor 23 (FGF23)-producing tumors that cause tumor-induced rickets/osteomalacia (TIO). Bone Rep. 2018;10:100192. doi: 10.1016/j.bonr.2018.100192. eCollection 2019 Jun. PMID: 30627598.
  45. Shinozaki-Ushiku A, Higashihara T, Ikemura M, Sato J, Nangaku M, Ushiku T, Fukayama M. Glomeruloid hemangioma associated with TAFRO syndrome. Hum Pathol. 2018;82:172-176. doi: 10.1016/j.humpath.2018.04.011. PMID: 29702119.
  46. Fukayama M, Miyagaki T, Akamata K, Suzuki S, Tanaka M, Sato S. Japanese familial anetoderma: A report of two cases and review of the published work.J Dermatol. 2018;45(12):1459-1462. doi: 10.1111/1346-8138.14672. PMID: 30320485.
  47. Enooku K, Kondo M, Fujiwara N, Sasako T, Shibahara J, Kado A, Okushin K, Fujinaga H, Tsutsumi T, Nakagomi R, Minami T, Sato M, Nakagawa H, Kondo Y, Asaoka Y, Tateishi R, Ueki K, Ikeda H, Yoshida H, Moriya K, Yotsuyanagi H, Kadowaki T, Fukayama M, Koike K. Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients. J Gastroenterol. 2018;53(12):1261-1275. doi: 10.1007/s00535-018-1472-0. PMID: 29749571.
  48. Yamagushi N, Mano T, Ohtomo R, Ishiura H, Almansour MA, Mori H, Kanda J, Shirota Y, Taira K, Morikawa T, Ikemura M, Yanagi Y, Murayama S, Shimizu J, Sakurai Y, Tsuji S, Iwata A. An Autopsy case of familial neuronal intranuclear inclusion disease with dementia and neuropathy.
  49. Intern Med. 2018;57(23):3459-3462. doi: 10.2169/internalmedicine.1141-18. PMID: 30101925.
  50. Sekimizu M, Yoshida A, Mitani S, Asano N, Hirata M, Kubo T, Yamazaki F, Sakamoto H, Kato M, Makise N, Mori T, Yamazaki N, Sekine S, Oda I, Watanabe SI, Hiraga H, Yonemoto T, Kawamoto T, Naka N, Funauchi Y, Nishida Y, Honoki K, Kawano H, Tsuchiya H, Kunisada T, Matsuda K, Inagaki K, Kawai A, Ichikawa H. Frequent mutations of genes encoding vacuolar H+ -ATPase components in granular cell tumors. Genes Chromosomes Cancer 2018. [Epub ahead of print] doi: 10.1002/gcc.22727. PMID: 30597645.
  51. Nejo T, Tanaka S, Ikemura M, Nomura M, Takayanagi S, Shin M, Ushiku T, Shibahara J, Saito N, Mukasa A. Maffucci syndrome complicated by three different central nervous system tumors sharing an IDH1 R132C mutation: case report. J Neurosurg. 2018. [Epub ahead of print] doi: 10.3171/2018.6.JNS18729. PMID: 30579273.
  52. Kume A, Yamashita H, Nishida M, Abe H, Fukayama M, Seto Y. A mass-forming cystic appearance of peritoneal recurrence of gastric adenocarcinoma Journal of Cancer Research and Practice 2018;5(4):169-171.doi: 10.1016/j.jcrpr.2018.06.002.
  53. Fukayama M, Kunita A, Kaneda A.Gastritis-Infection-Cancer Sequence of Epstein-Barr Virus-Associated Gastric Cancer. Adv Exp Med Biol. 2018;1045:437-457. doi: 10.1007/978-981-10-7230-7_20. PMID: 29896679.
  54. Nishioka Y, Shindoh J, Inagaki Y, Gonoi W, Mitsui J, Abe H, Yoshioka R, Yoshida S, Fukayama M, Tsuji S, Hashimoto M, Hasegawa K, Kokudo N. Host MICA Polymorphism as a Potential Predictive Marker in Response to Chemotherapy for Colorectal Liver Metastases. Dig Dis. 2018;36(6):437-445. doi: 10.1159/000490411. PMID: 29969766.
  55. Mizuno S, Nakai Y, Tanaka M, Ushiku T, Arita J, Hasegawa K, Fukayama M, Koike
    K. Reappraisal of the usefulness of percutaneous transhepatic cholangioscopy for indeterminate distal biliary strictures. J Gastroenterol Hepatol. 2019. [Epub ahead of print] doi: 10.1111/jgh.14588. PMID: 30669178.
  56. Kinoshita H, Hayakawa Y, Konishi M, Hata M, Tsuboi M, Hayata Y, Hikiba Y, Ihara S, Nakagawa H, Ikenoue T, Ushiku T, Fukayama M, Hirata Y, Koike K. Three types of metaplasia model through Kras activation, Pten deletion, or Cdh1 deletion in the gastric epithelium. J Pathol. 2019;247(1):35-47. doi: 10.1002/path.5163. PMID: 30168144.
  57. Shiratori H, Kawai K, Hata K, Tanaka T, Nishikawa T, Sasaki K, Kaneko M, Murono K, Emoto S, Morikawa T, Fukayama M, Nozawa H. Correlations between the Recurrence Patterns and Sizes of Lateral Pelvic Lymph Nodes before and after Chemoradiotherapy in Patients with Lower Rectal Cancer. Oncology. 2019;96(1):33-43. doi: 10.1159/000492493. PMID: 30212816.
  58. Sato K, Kawazu M, Yamamoto Y, Ueno T, Kojima S, Nagae G, Abe H, Soda M, Oga T, Kohsaka S, Sai E, Yamashita Y, Iinuma H, Fukayama M, Aburatani H, Watanabe T, Mano H. Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability-High Colorectal Cancers. Clin Cancer Res. 2019;25(1):378-389. doi: 10.1158/1078-0432.CCR-18-1574. PMID: 30279230.
  59. Tanaka M, Shibahara J, Ishikawa S, Ushiku T, Morikawa T, Shinozaki-Ushiku A, Hayashi A, Misumi K, Tanaka A, Katoh H, Sakuma K, Kokudo T, Inagaki Y, Arita J, Sakamoto Y, Hasegawa K, Fukayama M. EVI1 expression is associated with aggressive behavior in intrahepatic cholangiocarcinoma. Virchows Arch. 2019;474(1):39-46. doi: 10.1007/s00428-018-2476-0. PMID: 30349952.
  60. Nakayama A, Abe H, Kunita A, Saito R, Kanda T, Yamashita H, Seto Y, Ishikawa S, Fukayama M. Viral loads correlate with upregulation of PD-L1 and worse patient prognosis in Epstein-Barr Virus-associated gastric carcinoma. PLoS One 2019;14(1):e0211358. doi: 10.1371/journal.pone.0211358. eCollection 2019. PMID: 30695048.
  61. Sawada N, Nakao T, Daimon M, Nawata K, Tanaka M, Komuro I. Multiple calcified amorphous tumors in a patient with end-stage renal disease. J Echocardiogr. 2019. [Epub ahead of print] doi: 10.1007/s12574-019-00416-1. PMID: 30701486.
  62. Saito K, Nakai Y, Ushiku T, Saito T, Takahara N, Mizuno S, Kogure H, Koike K. Successful diagnosis of primary peritoneal serous carcinoma by endoscopic ultrasound-guided through-the-needle forceps biopsy. J Gastroenterol Hepatol. 2019. [Epub ahead of print] doi: 10.1111/jgh.14593. PMID: 30693562.
  63. Abe M, Watanabe K, Shinozaki-Ushiku A, Ushiku T, Abe T, Fujihara Y, Amano Y, Zong L, Wang CP, Kubo E, Inaki R, Kinoshita N, Yamashita S, Takai D, Ushijima T, Nagase T, Hoshi K Identification of a metastatic lung adenocarcinoma of the palate mucosa through genetic and histopathological analysis: a rare case report and literature review. BMC Cancer. 2019;19(1):52. doi: 10.1186/s12885-019-5277-1. PMID: 30634950.
  64. Fukayama M, Asano Y, Shinozaki-Ushiku A, Sato S. Estrogen dermatitis: Case report and examination of estrogen receptor-β in the skin. J Dermatol. 2019. [Epub ahead of print] doi: 10.1111/1346-8138.14750. PMID: 30628111.
  65. Bains S, Eguchi T, Warth A, Yeh YC, Nitadori JI, Woo KM, Chou TY, Dienemann H, Muley T, Nakajima J, Shinozaki-Ushiku A, Wu YC, Lu S, Kadota K, Jones DR, Travis WD, Tan KS, Adusumilli PS. Procedure-Specific Risk Prediction for Recurrence in Patients Undergoing Lobectomy or Sublobar Resection for Small (≤2 cm) Lung Adenocarcinoma: An International Cohort Analysis. J Thorac Oncol. 2019;14(1):72-86. doi: 10.1016/j.jtho.2018.09.008. PMID: 30628111.
  66. Sawada N, Nakao T, Daimon M, Nawata K, Tanaka M, Komuro I. Multiple calcified amorphous tumors in a patient with end-stage renal disease. J Echocardiogr. 2019. [Epub ahead of print] doi: 10.1007/s12574-019-00416-1. PMID: 30701486.
  67. Hakozaki M, Ito S, Fujii T, Kiya Y, Udagawa H, Fukayama M, Fukusato T. Combined hepatocellular-cholangiocarcinoma with angiosarcomatoid change: A case report with immunohistochemical study. Pathol Int. 2019;69(2):110-116. doi: 10.1111/pin.12755. PMID: 30672653.
  68. Okamoto H, Yoshimatsu Y, Tomizawa T, Kunita A, Takayama R, Morikawa T, Komura D, Takahashi K, Oshima T, Sato M, Komai M, Podyma-Inoue KA, Uchida H, Hamada H, Fujiu K, Ishikawa S, Fukayama M, Fukuhara T, Watabe T. Interleukin-13 receptor α2 is a novel marker and potential therapeutic target for human melanoma. Sci Rep. 2019;9(1):1281. doi: 10.1038/s41598-019-39018-3. PMID: 30718742.
  69. Kohsaka S, Tatsuno K, Ueno T, Nagano M, Shinozaki-Ushiku A, Ushiku T, Takai D, Ikegami M, Kobayashi H, Kage H, Ando M, Hata K, Ueda H, Yamamoto S, Kojima S, Oseto K, Akaike K, Suehara Y, Hayashi T, Saito T, Takahashi F, Takahashi K, Takamochi K, Suzuki K, Nagayama S, Oda Y, Mimori K, Ishihara S, Yatomi Y, Nagase T, Nakajima J, Tanaka S, Fukayama M, Oda K, Nangaku M, Miyazono K, Miyagawa K, Aburatani H, Mano H. Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin-fixed paraffin-embedded specimens. Cancer Sci. 2019. [Epub ahead of print] doi: 10.1111/cas.13968. PMID: 30737998.
  70. Shinagawa T, Hata K, Morikawa T, Matsunaga K, Emoto S, Murono K, Kaneko M, Sasaki K, Nishikawa T, Tanaka T, Kawai K, Nozawa H, Fukayama M, Ishihara S. Loss of RUNX3 Immunoreactivity in Non-Neoplastic Rectal Mucosa May Predict the Occurrence of Ulcerative Colitis-Associated Colorectal Cancer. Digestion. 2019. [Epub ahead of print] doi: 10.1159/000497272. PMID: 30763934.
  71. Watanabe K, Kage H, Shinozaki-Ushiku A, Kohsaka S, Takai D, Nakajima J, Miyagawa K, Aburatani H, Mano H, Nagase T. Spontaneous Transdifferentiation from Small Cell Lung Carcinoma to Squamous Cell Carcinoma. J Thorac Oncol. 2019;14(2):e31-e34. doi: 10.1016/j.jtho.2018.10.159. PMID: 30683296.
  72. Kadowaki H, Amiya E, Hoshino Y, Tamura M, Uehara M, Nakayama A, Nawata K, Domoto Y, Saeki T, Ono M, Komuro I. Enormous Aneurysm in Coronary Artery Fistula With Immunoglobulin G4-Related Disease. Can J Cardiol. 2019;35(2):230.e1-230.e3. doi: 10.1016/j.cjca.2018.11.030. PMID: 30760436.
  73. Hirakawa Y, Miura R, Sasaki Y, Yoshida Y, Mimura I, Katsura M, Shintani-Domoto Y, Ogawa M, Hayashi A, Nangaku M. Nutcracker Syndrome with the Superimposition of Thin Basement Membrane Syndrome. Intern Med. 2019;58(3):411-414. doi: 10.2169/internalmedicine.1433-18. PMID:30210125.
  74. Ebisawa K, Masamoto Y, Tokushige J, Nishi H, Honda K, Hinata M, Toyama K, Nangaku M, Kurokawa M. Tocilizumab for focal segmental glomerulosclerosis secondary to multicentric Castleman’s disease. Ann Hematol. 2019. [Epub ahead of print] doi: 10.1007/s00277-019-03616-y. PMID: 30761408.
  75. Moriguchi S, Uruga H, Fujii T, Yasunaga Y, Takahashi Y, Kishi K. Transformation of epidermal growth factor receptor T790M mutation-positive adenosquamous carcinoma of the lung to small cell carcinoma and large-cell neuroendocrine carcinoma following osimertinib therapy: an autopsy case report. Respirol Case Rep. 2019;7(3):e00402. doi: 10.1002/rcr2.402. PMID: 30828454.
  76. Kobayashi H, Makise N, Ushiku T, Ito N, Koga M, Shinoda Y, Tanaka S. Infiltrative nature of tumor-induced osteomalacia lesions in bone: Correlation between radiological and histopathological features. J Orthop Sci. 2019. [Epub ahead of print] DOI: 10.1016/j.jos.2019.02.005. PMID: 30797665.
  77. Aoki T, Yoshida S, Abe H, Ono S, Nakada A, Ota Y, Narita A, Yoshikawa T, Kinoshita H, Tsuji Y, Yamada A, Fujishiro M, Hirata Y, Fukayama M, Koike K. Analysis of predictive factors for R0 resection and immediate bleeding of cold snare polypectomy in colonoscopy. PLoS One 2019;14(3):e0213281. doi: 10.1371/journal.pone.0213281. PMID: 30822318.
総説・著書
英文
  1. Tetsuo Ushiku, Spiro C. Raftopoulos, Gregory Y. Lauwers, M. Priyanthi Kumarasinghe. Stomach: Neoplastic Patterns and Mimics. Endoscopic Biopsy Interpretation: A Practical Guide. 2019:157-187.
  2. Tetsuo Ushiku, Thomas Arnason. Pathology and Staging of Esophageal Adenocarcinoma Modern Thoracic Oncology (Volume 3). 2018:107-116.
和文
  1. 牧瀬 尚大. 平成29 年度日本病理学会100周年記念病理学研究新人賞 受賞体験記, 病理と臨床. 2019;37(1):99-101.
学会発表
国際学会
  1. 19th International Congress of Neuropathology, September 23-27, 2018. Tokyo, Japan.
    [Poster presentation]
    Masako Ikemura, Atsushi Kondo, Hiroyuki Abe, Tetsuo Ushiku, Shunsaku Takayanagi, Masahiro Shin, Shota Tanaka, Masashi Fukayama. An autopsy case of diffuse midline glioma around the foramen of Monro
  2. 11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine, Feb. 8-12, 2019. Maui, Hawaii, USA.
    [Poster presentation]
    Akiko Kunita, Miyako Fukasawa, Shu Nishida, Hiroyuki Abe, Tetsuo Ushiku, Masashi Fukayama. Establishment of human gastric organoids as a model of early neoplastic stages
国内学会,研究会

<教室に関連した主たる学会>

  1. 第107回日本病理学会総, 会2018年6月21日-23日 札幌
    [口演]
    牧瀬尚大、関水壮哉、小西英一、元井亨、久保崇、平岡伸介、深山正久、川井章、市川仁、吉田朗彦、H3K27me3の消失した脱分化型軟骨肉腫は 特徴的な臨床病理像を示す小群を形成する
    田中麻理子山内直子牛久哲男森川鉄平,有田淳一,阪本良弘,長谷川潔,深山正久.胆管がんにおける形態学的予後因子
    牧瀬尚大.脱分化ないし異所性分化を示す肉腫 におけるMDM2増幅とH3K27me3消失の 診断的意義に関する研究
    岩﨑晶子牛久哲男山澤翔阿部浩幸牛久綾深山正久.胃癌におけるSWI/SNF複合体異常は腫瘍内不均一性が高くEBV・MSI陽性群で高頻度に認められる
    [示説]
    池村雅子深山正久.偶発性Lewy病(初期Lewy小体病)における異常アルファシヌクレインの全身臓器への沈着の検討
    村田 翔平, 阿部 浩幸, 牛久 綾, 牛久 哲男, 小林 寛, 間野 博行, 深山 正久.異型が目立ち診断に苦慮した軟部組織血管線維腫の一例
    大井手 慶, 阿部 浩幸, 山澤 翔, 牛久 哲男, 深山 正久.胃癌組織におけるEZH2の臨床病理学的意義およびARID1A、BAP1との関係について
    阿部 浩幸, 深山 正久, Vieth Michael.バレット食道の表在腺癌におけるp53、ARID1A、EZH2の免疫組織学的発現検討
    沼倉 里枝, 西東 瑠璃, 富樫 有紗, 渡部 朱織, 渡邉 雅人, 菊地 良直, 宇於崎 宏.胃癌間質におけるCD90発現の意義
    西東 瑠璃, 宇於崎 宏, 渡邉 雅人, 本田 絢子, 北國 圭一, 園生 雅弘, 村山 繁雄.Creutzfeldt-Jakob病(MM2-thalamic type)の1剖検例
    安永瑛一,宇留賀公紀,藤井丈士,中村信之,岸一馬.EGFR T790M変異と小細胞癌への形質転換を認めた肺腺扁平上皮癌の1剖検例
  2. 第77回日本癌学会学術総, 会2018年9月27日~29日 大阪国際会議場 リーガロイヤルホテル大阪
    [示説]
    星大輔、喜多絵美里、丸喜明、筆宝義隆.Organoid culture of pancreatic acinar cell carcinoma
  3. 第57回日本臨床細胞学会秋期大, 会2018年11月17日~18日 横浜
    [口演]
    牛久綾, 腺房細胞癌の細胞診断
  4. 第64回日本病理学会秋期特別総, 会2018年11月22日-23日 広島県呉市
    [口演]
    阿部浩幸, 黒瀬優介, AIによる胃生検病理診断支援システム開発
    [示説]黒江崇史, 伊藤慎治, 岡根谷利一, 長嶋洋治, 深山正久, 藤井丈士, 嫌色素性腎細胞癌・オンコサイトーマ様亜型と考えられた一例
  5. 第81回 日本病理学会 関東支部 学術集, 会2018年12月8日 神奈川県川崎市
    [口演]
    田秀,沼倉里枝,阿部浩幸,佐々木欧,久保かなえ,牛久哲男,藤尾圭志,深山正久.再発性多発軟骨炎の合併が疑われた多発⾎管炎性肉芽腫症の一剖検例
  6. 第15回日本消化管学会総会学術集, 会2019年2月1日~3日 佐賀
    [口演]
    牛久哲男.ワークショップ基調講演:免疫チェックポイント阻害薬時代の消化管病理学
  7. 第91回日本胃癌学会総,会2019年2月27日~3月1日 沼津
    [口演(英語)]
    Tetsuo Ushiku. Panel Discussion: Pitfalls in the interpretation of gastric biopsy―importance of clinicopathological correlation

<その他の学会・研究会、学術的活動>

  1. 日本癌病態治療研究会, 2018年5月31~6月1日 ホテルポートプラザちば
    [示説]
    星大輔、高橋寿枝、 布袋屋修、井下尚子. A型胃炎(自己免疫性胃炎)を背景とした胃神経内分泌腫瘍(NET)の1例と13例の免疫組織化学的検討
  2. 第6回内科と外科のコ・オペレーション, 2018年7月5日, 東京牛久哲男. 特別講演「30分で分かるEBV関連胃癌のすべて」
  3. 第15回EBウイルス研究会, 2018年7月14日 山口県宇部市
    [口演]
    中山敦仁, 阿部浩幸, 国田朱子, 深山正久. EBV関連胃癌におけるウイルスコピー数とその臨床病理学的意義
  4. 第27回日本がん転移学会学術集会・総会, 2018年7月19日~20日 横浜
    [示説]
    山田慎二、国田朱子、深山正久、西岡安彦、加藤幸成.ポドプラニンに対するがん特異的認識抗体の抗腫瘍効果および安全性評価
  5. 平成30年度文部科学省新学術領域研究 先端モデル動物支援プラットフォーム 若手支援技術講習会、2018年9月6日~8日 蓼科グランドホテル滝の湯
    [示説]
    星大輔、喜多絵美里、丸喜明、筆宝義隆.Organoid culture of pancreatic acinar cell carcinoma
  6. 第59回千葉消化器疾患研究会, 2018年9月7日,千葉
    牛久哲男.教育講演 「消化管腫瘍個別化医療の現在」
  7. 第37回日本認知症学会学術集会, 2018年10月12日~14日 札幌
    [示説]
    箱崎眞結,仲泰史,田尻智也,深山正久,橋本唯史,岩坪威.アミロイド斑蓄積のseedとして働く可溶性Aβオリゴマーの同定
  8. 東京大学病理検査室60周年・病理部40周年記念「次世代病理診断を考える」シンポジウム,2018年10月20日 東京
    牛久綾 ゲノム中核病院における病理診断
    阿部浩幸 AI開発と病理診断
    佐々木毅 遠隔病理診断の将来
    牛久哲男 ロボット技術、透明化と病理診断
    池村雅子.病理解剖と研修医教育
    金子伸行.ISO15189と病理検査室の将来
    鈴木由美恵.病理専門技師、パソロジーアシスタントを考える
    竹内裕子.大学病院における細胞診
    深山正久.今後に託す思い
  9. 2018年度日本がん治療認定医機構教育セミナー,2018年10月27日,大阪
    牛久哲男.病理学
  10. 第16回がんとハイポキシア研究会,2018年11月9日~10日 ホテルグリーンタワー幕張
    [示説]
    星大輔、喜多絵美里、丸喜明、筆宝義隆.Organoid culture of pancreatic acinar cell carcinoma
  11. 2018秋基礎医養成セミナー 2018年11月9日、浜松
    牛久哲男.特別講演「変化する胃癌」
  12. 第16回上部消化管外科懇話会,2018年11月24日,東京牛久哲男.特別講演「病理からみた胃腫瘍における個別化医療の現状と課題」